Prayer is like breathing. For Christians, it is one of the fundamental aspects of their human existence. In prayer, they find not only peace and comfort, security and hope, but also come to understand who God is for them. It is not uncommon for prayer to be intertwined with a deep longing for meaning in one’s life. Especially in today's world, a time of increasing anonymity and mutual alienation, prayer can serve as a guide to a fulfilled life. This handbook demonstrates the value and significance of prayer. With their concise and well-founded contributions, the authors enable interested readers to engage in a comprehensive critical-constructive examination of the topic "praying and prayer" from various scientific perspectives, while also providing encouragement and inspiration for practical application in the current societal situation.