Confront your fears, or they will do with you as they please. For thousands of years, the Sisterhood of the Bene Gesserit has operated behind the scenes of the Empire, controlling the genetic interconnections of the ruling houses and dedicating themselves to the breeding of special talents. However, during the time of the great diaspora, a new enemy has emerged for the order: the Honored Matres. Driven from Arrakis, the desert planet, the Bene Gesserit offer negotiations to the Honored Matres—while simultaneously plotting their destruction. But they encounter an equally formidable opponent. Ultimately, it becomes clear that this conflict has been long in the making, laying the groundwork for the future of human civilization.