The book "High-Performance Scientific Computing" presents the revised proceedings of the first JARA High-Performance Computing Symposium, which took place in October 2016 in Aachen. It includes 21 selected and peer-reviewed contributions that emerged from 26 submitted papers. The topics covered are diverse, ranging from methods and strategies for coupling in Computational Fluid Dynamics (CFD) to issues of performance portability and applications in high-performance computing. Additionally, the topic of provenance tracking for large-scale simulations is also addressed. This specialized book is aimed at scientists and practitioners who wish to engage with the latest developments and challenges in the field of high-performance computing.