Most people spend a significant portion of their lives at work. The workplace and social relationships in the work environment can represent important resources that should be considered in psychotherapeutic treatment. However, conflicts and anxieties at work, incapacity to work, job insecurity, and unemployment can also negatively impact mental well-being and contribute to the onset, maintenance, or worsening of a mental disorder. Therefore, workplace-focused interventions should hold particular significance in the psychotherapeutic treatment of patients. The aim of this volume is to provide current information on the psychotherapeutic treatment of employed patients with mental disorders. The volume explains how workplace-related factors play a role in this context.