The serial killer Francis Ackerman Jr. has often helped his brother, government agent Marcus Williams, and his colleagues solve the most gruesome crimes. By now, the agent team of the Shepherd Organization has even grown somewhat dear to the killer. When Shepherd agent Maggie falls into the hands of the notorious serial killer "The Taker," Ackerman and Williams pursue the kidnapper into a Native American reservation in New Mexico. To lure him out of hiding, Ackerman instigates a bloody war—a war that will claim many victims on both sides.