The book "Immune Regulation and Immunotherapy in Autoimmune Disease" offers a comprehensive analysis of the clinical and immunological aspects of autoimmune diseases, with a particular focus on multiple sclerosis (MS). In a rapidly evolving research field, it sheds light on innovative concepts related to autoimmune mechanisms and presents a variety of new treatment methods that were considered science fiction just two decades ago. The 24 chapters, written by leading experts, aim to convey both the current understanding of autoimmune mechanisms and immune regulation, as well as the latest advancements in immunotherapy. The book is intended for researchers and clinicians and provides not only a thorough overview of recent developments but also reflects current opinions and concepts that influence our thinking about the mechanisms of the disease and the treatment of MS patients. Many of the topics discussed are based on recent studies that challenge traditional views and highlight the heterogeneity of MS.