This monograph provides a current overview of the possibilities and limitations of immunohistochemistry in clinical and experimental neuro-oncology, based on extensive original research. The focus is on the significance of detecting differentiation markers and proliferation-associated antigens for the differential diagnosis and tumor grading of nervous system tumors. Additionally, new results on the detection of oncoproteins, growth factors, and receptors, as well as findings from experimentally induced tumors in rats, are presented. The text is supplemented by illustrations and tables. Thus, the book offers a concise summary of the topic for pathologists and clinicians interested in neuro-oncology.