The book "Integrated Circuit and System Design. Power and Timing Modeling, Optimization and Simulation" offers a comprehensive collection of research papers presented at the PATMOS 2007 workshop. This workshop, organized by Chalmers University of Technology, has established itself as a significant platform for the exchange of ideas and techniques in the field of integrated circuits and systems. The contributions in this volume cover a wide range of topics addressing the challenges of modern circuit design, particularly concerning timing, performance, and energy consumption. The authors, including Lars Svensson and Nadine Azemard, have explored the latest methods for modeling, analysis, and optimization in nanometer technology. The collected works provide valuable insights into current trends and technologies that are crucial for the development of future integrated circuits.