The well-being of children is discussed as a general framework from various disciplines and made applicable in terms of promoting a culture of awareness in institutions. In collaboration between science and educational practice, a practical handbook has been created. Questions regarding child welfare and child protection are currently the subject of intense controversy. There is agreement that institutions must have conditions in place to safeguard child welfare and prevent any form of child abuse. Often, silence about abuse complicates the assurance of child welfare. For this reason, the authors discuss interdisciplinary educational, structural, and organizational aspects that promote a culture of awareness. This handbook has emerged from collaboration with professionals from both science and practice.