What does a contemporary and rational therapy for Multiple Sclerosis (MS) look like? Given the dynamic development of therapies and the availability of various medications for the immunotherapy of MS, it is becoming increasingly difficult to keep track and adequately advise patients on their journey through the disease. This volume supports clinicians in managing MS patients. Using case studies, typical clinical questions are outlined, strategies explained, and relevant background information provided to facilitate shared therapeutic decision-making. In addition to modern immunotherapies, symptomatic, non-pharmacological, and complementary therapy concepts are also presented.