Multiple sclerosis is one of the neurological disorders that has fundamentally changed in recent years in terms of pathogenetic understanding, therapy, diagnostics, and care. This volume presents these advancements in a clear and application-oriented manner and includes all relevant aspects of the current knowledge on multiple sclerosis. It serves not only as a reference work but also as a guide and action manual for concrete recommendations on therapy and diagnosis. The combination of these criteria, along with the strong emphasis on practical questions and aspects of patient care, makes this monograph an important companion in everyday life and is unique in the German-speaking world.