This textbook provides a fundamental introduction to the programming environment MATLAB and demonstrates how it can be effectively used for numerical and symbolic computation and visualization to solve problems in mechanical engineering. The focus is on mathematical and physical modeling, as well as the calculation and simulation of dynamic systems. Application examples from the fields of machine dynamics, vibration theory, and mechatronics facilitate understanding. The current edition includes additional examples and has updated existing material with the latest software version. Programs and further exercises related to each chapter can be found in the book.