The book "Multidisciplinary Methods for Analysis, Optimization and Control of Complex Systems" offers a comprehensive examination of the methods and tools used for the analysis, optimization, and control of complex systems. It is based on the insights and collaboration within the MACSI-net, a European network dedicated to solving challenging problems in both industry and academia. The content of the book is the result of a summer academy focused on promoting interaction between industry and science. The authors, including Vincenzo Capasso, highlight the necessity of combining various disciplines such as applied mathematics, scientific computing, and engineering to address the challenges of modern society. The book is aimed at young researchers and professionals who are dealing with the complexity of systems and wish to develop innovative approaches to problem-solving.