"Neuronal Death by Accident or by Design" is a specialized book that explores the complex mechanisms of cell mortality, particularly in the context of neurodegenerative diseases. It provides a comprehensive analysis of the role of mitochondria in activating the final phases of cell death. The book is divided into two main parts: the first part focuses on the mechanisms that regulate cell mortality, while the second part examines the specific damages in human and animal models of neurodegenerative diseases. By linking basic research with clinical insights, the book aims to achieve a deeper understanding of the pathophysiology of these diseases. The authors hope that the findings will lead to the development of more targeted and effective therapies. With an interdisciplinary approach, the book will be of interest to both researchers and professionals in the fields of medicine and nursing.