Now newly available in English translation! No organic genius has fallen from the sky – only practice makes perfect! To avoid losing track in the infinite variety of synthesis possibilities and reagents in organic chemistry, persistent self-study of original literature or books is just as important as – practice, practice, practice. A popular and successful method in research groups that helps solidify knowledge of synthesis strategies and reactivities is seminars where synthesis tasks must be solved. From such a seminar, eight doctoral candidates from Göttingen developed a unique and engaging workbook for organic synthesis. Based on total syntheses of well-known natural substances, students acquire new knowledge step by step and stage by stage of synthesis. Before the diploma examination or rigorous examination, aspiring chemists should prepare thoroughly.