On a completely ordinary morning filled with heroic deeds, Spider-Man receives a troubling message from the Fantastic Four and Namor: the mysterious underwater city of Atlantis has vanished, and the heroes need Spidey's help to find it. The web-slinger embarks on the uncertain mission, hoping not to disappoint his friends. However, when more superheroes suddenly start disappearing throughout the city, he realizes that superpowers alone may not be enough to succeed. Together with fantastic heroes like Ant-Man, Wasp, and She-Hulk, writer and artist Mike Maihack sends Spider-Man into the wondrous quantum realm.