Optimize the supply and safety of your patients with Patient Blood Management. Patient Blood Management (PBM) is a multidisciplinary, evidence-based treatment concept for the optimal use of blood products. It prevents shortages in the supply of donor blood, minimizes risks and complications associated with blood transfusions, and reduces costs. This work presents the PBM concept in detail and in an understandable way, focusing on its three pillars: optimization of erythrocyte volume, minimization of bleeding and blood loss, and increasing and utilizing anemia tolerance. It provides quick guidance and offers concrete recommendations for practical implementation. New in the 2nd edition: - Establishment of a PBM database - Implementation of PBM in hospitals - Implementation of PBM in Europe - Gender-specific differences - PBM in non-surgical areas.