The book "Peptidomimetics Protocols" offers a comprehensive analysis of the role of peptides in pharmaceutical research and development. It highlights the challenges associated with using natural peptides as drugs and discusses innovative approaches to overcoming these hurdles. In particular, it addresses the need to improve the stability and bioavailability of peptides to make them more effective as therapeutic agents. The work combines modern synthetic and medicinal chemistry to present new methods for producing peptidomimetics that mimic the physiological properties of peptides but exhibit enhanced characteristics. The various chapters provide valuable insights into the latest developments and techniques in this dynamic research field and are of interest to both professionals and students.