There is hardly any physical ailment that is not triggered or worsened by tobacco use. Nevertheless, there are about 18 million smokers in Germany. Most smokers feel dissonance regarding their smoking behavior and would like to change it. However, only around 5% of all attempts to quit smoking are successful. Therefore, smokers who, despite good motivation, struggle to quit are advised to seek professional help. The book outlines the fundamentals of tobacco addiction and subsequently explains the therapeutic approach within the framework of individual treatment. It presents in detail interventions for motivation, preparation, and maintaining a smoke-free life. It covers classical cognitive-behavioral self-control methods, medication treatment, as well as modern solution-oriented approaches.