The second volume of the new series "Anthropological Psychiatry" exemplifies how dependent good psychiatric research and practice are on thorough reflection about our understanding of humanity and the advancement of our knowledge about human existence and functioning. With Andreas Heinz and Thomas Bock, one of the most experienced German professors meets the "father" of the trialogue. The result is a multifaceted perspective on psychoses that opens up new options for action. In and through psychoses, all participants encounter deeply human themes that touch us all at our core. Psychoses confront us with strangeness and alienation, with the loss of the taken-for-granted, and with confusion and turmoil in the search for meaning. At the same time, they also allow and demand.