To make the quality of healthcare measurable and verifiable, quality characteristics must be identified and described. The general requirements for a quality management system are defined in ISO 9001, which serves as the basis for a sector-specific standard of the quality management system for healthcare organizations. The author explains the contents of both standards in a target group-oriented manner and compares them. A tabular comparison of the requirements from DIN EN ISO 9001:2015 and DIN EN 15224:2012 highlights similarities and differences. All relevant requirements are printed as quotes. Numerous tips and examples for practical implementation facilitate the transition and integration of the different quality management systems. Additionally, template forms for frequently needed procedural and work instructions are provided.