Ever caught yourself screaming, "I could just kill that teacher"? What would it take to justify such antisocial behavior and weeks of detention? Especially if he's the best teacher you've ever had? Giving you an "F" on a quiz? Mispronouncing your name during roll call...again? How about blowing up the moon and threatening to do the same to Mother Earth—unless you take him out first?! Plus a reward of a cool 100 million from the Ministry of Defense! Okay, now that you're committed... How are you going to pull this off? What does your pathetic class of misfits have at their disposal to combat Teach's alien technology, bizarre powers and...tentacles?

A sexy new teacher comes to Class 3-E to do the students' job for them. When the 3-E students begin exhibiting signs of self-esteem, Principal Asano demands that Koro Sensei crush their spirits so they continue to set a bad example for the rest of the school to rise above. Then a class field trip goes terribly wrong when two 3-E girls are abducted. Who will come to their rescue?.