"Spiritual Care" helps to understand and professionally address the existential and spiritual needs of patients as well as their relatives and caregivers. This book conveys the approach of Spiritual Care in a pluralistic society from the perspective of Practical Theology. Precise observations of disease progressions, everyday clinical life, and public discussions are combined with theological analyses. They lead to a better understanding of health-related spirituality between uncertainty and determinability. Concrete references to the unique contribution of pastoral care to spiritual guidance make it clear that pastoral care is indispensable for organizing spiritual support in 21st-century healthcare: Spiritual Care.