This book offers a practice-oriented introduction to the specifics of psychotherapy with late adolescents and young adults. It is written for analytical and depth-psychological psychotherapists in training and practice, as well as for practitioners of other theoretical orientations. Late adolescence is a time of farewell to parents, to a societal protective space that until now allowed actions without far-reaching consequences, and to compensatory notions of omnipotence and grandiosity. The therapeutic engagement with patients aged 18 to 25 presents special demands on therapists and unfolds within the tension between diagnostic uncertainty and intense countertransference reactions from the therapists or the therapeutic team, as well as speechlessness and ambivalence towards the therapeutic process.