For more than 20 years, genetic engineering methods have been established in medical and pharmaceutical research as well as in degree programs in biology and biochemistry. Knowledge of legal frameworks and laboratory safety is the most important prerequisite for these applied methods. This legal guide for scientists supports students, doctoral candidates, researchers at universities, and laboratory operators in the industry with practical examples in the application of genetic engineering law in all important practical issues related to the Genetic Engineering Act and its regulations. The key legal requirements are presented in detail, including current assessments from the ZKBS and recent case law. The authors include an experienced practitioner and university lecturer, as well as a specialized legal and expert attorney.