The book "Immunoinformatics: Predicting Immunogenicity In Silico" offers a comprehensive introduction to the emerging discipline of immunoinformatics. It is aimed at researchers interested in the application of computational techniques in immunology and vaccine development. The content is divided into four main sections that address various aspects of immunoinformatics. Readers will gain valuable insights into the use of databases, the definition of HLA supertypes, the prediction of peptide-MHC bindings, and the analysis of other properties of the immune system. This specialized book combines the expertise of laboratory and computer scientists and serves as a valuable resource for anyone dealing with immunological questions.