Based on an online survey and a case study analysis, Jens Lehnen examines the collaboration between companies and lead users—advanced users who experience future needs earlier than the majority and often innovate themselves. He further develops the theoretical methodology of the lead user approach and creates connections to other disciplines such as agile project management. Collaboration with lead users is highly valuable for companies' innovation development, which is why the author concludes by defining a best practice for the effective application of the lead user approach in practice.