The book "Lower Extremity Arterial Disease" offers a comprehensive analysis of lower extremity disease, which is often associated with coronary heart disease and general atherosclerosis. It is estimated that around 10 million people in the United States suffer from this condition, with only one in four affected individuals surviving more than ten years. In this specialized book, leading experts from the fields of cardiovascular medicine, hypertension, vascular surgery, vascular radiology, and vascular physiology have collaborated to shed light on the current state of research regarding atherosclerosis in the arteries of the legs and feet. The authors thoroughly discuss the main symptoms, diagnostic methods, and therapeutic advancements, including non-invasive angiography and specific drug therapies. Additionally, the epidemiology of the disease, its risk factors, and the necessity for early diagnosis are addressed.