The book "Macroscale Models of Flow Through Highly Heterogeneous Porous Media" offers a comprehensive examination of the modeling of transport processes in highly heterogeneous media. It pursues two main objectives: Firstly, it presents new findings in the field of modeling transport through heterogeneous media based on homogenization theory. Secondly, it introduces various mathematical models that investigate the properties of transport and develop methods for calculating effective parameters of the averaged media. The authors illuminate the simulation of cell problems and utilize innovative models to address practical challenges. The treatment of high heterogeneity through the homogenization process leads to non-local phenomena and opens up the possibility of developing a new, dynamic theory of transport in porous media. This specialized book is aimed at scientists and professionals dealing with transport technology and its associated challenges.