The textbook "Medical Informatics: Knowledge Management and Data Mining in Biomedicine" offers a comprehensive introduction to the fundamentals of knowledge management and data analysis in the field of biomedicine. It covers both the basic concepts and the latest research findings and techniques developed in this dynamic field. Through detailed case studies, the practical applications of these concepts are illustrated, enabling professionals and researchers to better understand and leverage the possibilities of informatics in biomedicine. The book is aimed at a broad audience of medical professionals and researchers who wish to engage with the challenges and opportunities of modern biomedical informatics.