This book describes the path ahead. It combines system transformation research with political economy and change leadership insights when discussing the need for a great mindshift in how human wellbeing, economic prosperity, and healthy ecosystems are understood if the great transformations ahead are to lead to more sustainability. It shows that history is made by purposefully acting humans and introduces transformative literacy as a key skill in leading the radical incremental change strategies that wicked problems require, illustrating their nature through mapping pioneering practices and commonalities.