The patellofemoral joint section is a significant source of persistent discomfort in artificial knee joint replacements, which can lead to further surgical revisions in a variety of patients. Against the backdrop of clinical long-term observations, experimental studies on the blood supply to the patella and the peculiarities of its mechanical loading situation are presented. The three-dimensional structure of the blood supply to the kneecap is illustrated for the surrounding soft tissues and the interior of the bone. The patellofemoral contact zones in various prostheses, with and without patellar surface replacement, are determined and described along with the load parameters in the extensor mechanism in a mathematical model of the patellofemoral joint as an asymmetric disc bearing. The book presents considerations that should be taken into account in the design of.