The book "U- and E-Service, Science and Technology" offers a comprehensive analysis of the future generation of information technologies (FGIT) and their interdisciplinary approaches. It highlights how advancements in one area of FGIT can be transferred to other disciplines and promotes the exchange of ideas and results among various fields. The publication is based on the insights from the first Mega Conference FGIT 2009, which focused on the hybridization of technologies. By combining concepts from different disciplines, it emphasizes the potential for innovative solutions and new principles that can be applied throughout the IT landscape. The contributions come from various international conferences addressing topics such as software engineering, life sciences, database theory, and network security. The editors are renowned experts in their field, underscoring the quality and relevance of the content.