In this book, Markus Bergmeier illustrates through three studies that the systematic design and coordination of distribution systems can lead to sustainable profit increases in companies. The first study links game-theoretical modeling with an empirical application, allowing for the simulation and evaluation of complex distribution system design options before they are implemented. The decision support system developed and tested in the second study can enhance the quality of dynamic pricing in distribution systems and reduce systematic judgment biases among sales managers. The third study identifies key factors influencing the popularity of online deals and assists manufacturers and retailers in optimizing promotional activities.