Few embody the essence of a resilient person as much as Samuel Koch. Anyone who doesn't lose their zest for life after a tragic setback like the fall during "Wetten dass..?" must surely know the secret of resilience – the inner strength that everyone desires and which entire fields of research focus on. With his uniquely dry humor, Samuel examines the current findings in resilience research and poses intriguing questions: Are the often-cited "pillars of resilience" perhaps standing on rather shaky ground? Can one truly cultivate optimism and a "now more than ever" mentality, or do we need entirely different approaches than previously thought? Prof. Dr. Gerald Hüther, the renowned neurobiologist, joins Samuel Koch in exploring what truly strengthens us.