Nonprofit organizations (NPOs) are currently facing a variety of challenges. This collection addresses these issues by adopting a case study perspective. It illustrates, through numerous examples, how NPOs can respond to changing conditions in different contexts. The cases demonstrate how problems are tackled in practice, the difficulties that arise, and how these can be successfully managed. A wide range of fields of activity, issues, and solution approaches are covered. The focus is less on the large organizations in the NPO sector in Germany and more on the smaller organizations, their needs, innovative approaches, and problem-solving strategies.