The Ultegra 10-speed cassette is available in various gradations and meets the demands of a wide range of riders, including juniors. It is compatible with Shimano 9-speed hubs and should only be used with a super narrow 10-speed chain.

The models CS-6600 (14-25, 15-25, 16-27) are not compatible with triple gear systems, as the shifting function would be impaired.