This 64GB memory is 100% compatible with Cisco UCS C460 M4 Xeon E7-x800 V3.

Information on memory configuration: The following technical specifications should be considered in advance: RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM) RAM can be installed in the device. LRDIMM memory is recommended when large memory capacities are to be achieved. RDIMM memory modules cannot be mixed with LRDIMM memory. If a memory upgrade is to be performed with the existing RAM, it must be checked which memory technology (RDIMM / LRDIMM) is present. When using a multiprocessor system, the memory slots should always be populated identically for each CPU. Memory slots without a processor should not be populated. A higher memory clock of the memory module automatically adjusts to the memory clock specified by the system. This can especially be the case with larger capacities.