Yes, you can format the external hard drive with exFAT. The exFAT format is often recommended if you want to use the hard drive with both Windows and Mac, as it supports files larger than 4 GB and is compatible with both operating systems. Formatting to exFAT can be done with tools such as the MiniTool Partition Wizard, as Windows' own tools sometimes have limitations. There are no restrictions or loss of warranty by formatting to exFAT on this hard drive.