Merck is the oldest pharmaceutical-chemical company in the world. It developed into a global corporation from a Darmstadt pharmacy that Jacob Friedrich Merck received the pharmacist's license for in 1668. This book tells the 350-year history of the company for the first time in its entirety and based on all the available sources, as well as the newest research in business history. For a long time, family-owned companies were regarded as a dying breed. The future seemed to belong to joint-stock companies with an anonymous stockholder structure. Yet there are numerous successful counterexamples in Germany, such as Bosch, C&A, and Bertelsmann. Merck, too, counts among them. How did the Merck family manage to keep the company in its possession for 13 generations through all the political ruptures and historical crises and turn it into a global leader among science and technology firms? With this as their central question, four acclaimed historians recount the fascinating history of the Merck company between 1668 and 2018, embedding it in the eventful course of world history.